Résumé:
This work present a preparation and characterization of polymer films based on
methylene blue, alginate, agar, starch, glycerol and citric acid for the local treatment of
wounds.
In the first part we addresse traditional and current wound and treatment issues,
highlighting challenges in chronic wound treatment and advanced film systems for wound
treatment.
In the second part we intrdoduce polymer-based pharmaceutical films with methylene
blue as effective alternatives for administering wound treatment.
In the result we have films formation confirmed by IR spectroscopy(C=O, 1602cm-1
),
the crosslinking percentage (27⸓ for film 1, 80⸓for film2). For mthylene blue release, results
indicate the controlled release with (8.9 10-3 mg/ml) at (240 min) and (8.6 10-3 mg/ml) at (150
min) for film1 and film2 respectively.
